
Twitch Build
the Plague Rat
A Zaunite plague rat by birth, but a connoisseur of filth by passion, Twitch is not afraid to get his paws dirty. Aiming a chem-powered crossbow at the gilded heart of Piltover, he has vowed to show those in the city above just how filthy they really are. Always a sneaky sneak, when he's not rooting around in the Sump, he's digging deep into other people's garbage for discarded treasures… and perhaps a moldy sandwich.
Twitch Bot Build
The most played Twitch Bot build on patch 26.21 runs Lethal Tempo with Triumph, Legend: Alacrity and Cut Down, plus Axiom Arcanist and Gathering Storm from the secondary tree. Take Flash and Barrier. Start with Doran's Bow and Health Potion, then build The Collector, Berserker's Greaves and Fiendhunter Bolts, followed by Infinity Edge, Lord Dominik's Regards, Bloodthirster and Guardian Angel. Max E (Contaminate) first, then Q (Ambush), then W (Venom Cask). It has a 51.6% win rate and a 5.7% pick rate.
Runes
Primary
Lethal Tempo
Attacking an enemy champion grants you Attack Speed, up to 6 stacks. At max stacks, deal bonus adaptive damage On-Attack.
Lethal Tempo
Attacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged] bonus adaptive damage On-Attack, increased by 1% per 1% Bonus Attack Speed.
Triumph
Takedowns restore 5% of your missing health and grant an additional 20 gold.
Triumph
Takedowns restore 5% of your missing health, 2.5% of your max health, and grant an additional 20 gold. 'The most dangerous game brings the greatest glory.' —Noxian Reckoner
Legend: Alacrity
Takedowns on enemies grant permanent Attack Speed.
Legend: Alacrity
Gain 3% attack speed plus an additional 1.5% for every Legend stack (max 10 stacks). Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Cut Down
Deal more damage to high health enemy champions.
Cut Down
Deal 8% more damage to champions who have more than 60% health.
Secondary
Axiom Arcanist
Your Ultimate has increased damage, healing, and shielding. Scoring a takedown on an enemy champion reduces your Ultimate's current cooldown.
Axiom Arcanist
Your Ultimate has 12% increased damage, healing, and shielding. (AoE damage is reduced to a 8% increase) Scoring a takedown on an enemy champion reduces your Ultimate's current cooldown by 7%.
Gathering Storm
Gain increasing amounts of AD or AP, adaptive over the course of the game.
Gathering Storm
Every 10 min gain AP or AD, adaptive. 10 min: + 8 AP or 5 AD 20 min: + 24 AP or 14 AD 30 min: + 48 AP or 29 AD 40 min: + 80 AP or 48 AD 50 min: + 120 AP or 72 AD 60 min: + 168 AP or 101 AD etc...
Summoner Spells
Flash
Cooldown 300s
Flash
Cooldown 300s
Teleports you a short distance toward your cursor.
Barrier
Cooldown 180s
Barrier
Cooldown 180s
Gain a brief Shield.
Skill Priority
EContaminate
Cooldown 12/11/10/9/8s · 50/60/70/80/90 Mana
Twitch wreaks further havoc on poisoned enemies with a blast of his vile diseases.
QAmbush
Cooldown 16s · 40 Mana
Twitch becomes Camouflaged for a short duration and gains Move Speed. When leaving Camouflage, Twitch gains Attack Speed for a short duration. When an enemy champion with Deadly Venom dies, Ambush's cooldown is reset.
WVenom Cask
Cooldown 13/12/11/10/9s · 70 Mana
Twitch hurls a cask of venom that explodes in an area, slowing targets and applying deadly venom to the target.
Item Build
Full build 20,150gStarting Items
Doran's Bow
400g
Doran's Bow
- 8 Attack Damage
- 15% Attack Speed
- 1.5% Omnivamp
Health Potion
2 Ă— 50g
Health Potion
Consume Restores 120 Health over 15 seconds.
Core Build
1The Collector
3,000g50 AD · 10 Lethality · 25% Crit
Death · Taxes
The Collector
3,000g- 50 Attack Damage
- 10 Lethality
- 25% Critical Strike Chance
Death Your damage executes champions that are below 5% Health. Taxes Champion kills grant 25 bonus gold.
2Berserker's Greaves
1,100g30% AS · 45 MS
Berserker's Greaves
1,100g- 30% Attack Speed
- 45 Move Speed
Enhances Move Speed and Attack Speed
3Fiendhunter Bolts
2,650g45% AS · 25% Crit · 4% MS
Night Vigil · Opening Barrage
Fiendhunter Bolts
2,650g- 45% Attack Speed
- 25% Critical Strike Chance
- 4% Move Speed
Night Vigil Gain 30 Ultimate Ability Haste. Opening Barrage After casting your Ultimate, your next 3 basic attacks gain 50% Attack Speed and Critically Strike for 80% of your normal Critical Strike damage for 8 seconds. If an attack would already Critically Strike, instead it deals 15% bonus true damage.
4Infinity Edge
3,500g75 AD · 25% Crit · 30% Crit Dmg
Infinity Edge
3,500g- 75 Attack Damage
- 25% Critical Strike Chance
- 30% Critical Strike Damage
Massively enhances critical strikes
5Lord Dominik's Regards
3,300g35 AD · 35% Armor Pen · 25% Crit
Giant Slayer
Lord Dominik's Regards
3,300g- 35 Attack Damage
- 35% Armor Penetration
- 25% Critical Strike Chance
Giant Slayer Deal up to 15% bonus damage against champions based on their bonus Health. Maximum damage bonus reached at 1500 bonus Health.
6Bloodthirster
3,400g80 AD · 15% Life Steal
Ichorshield
Bloodthirster
3,400g- 80 Attack Damage
- 15% Life Steal
Ichorshield Convert excess healing from your Lifesteal to a Shield.
7Guardian Angel
3,200g55 AD · 45 Armor
Rebirth
Guardian Angel
3,200g- 55 Attack Damage
- 45 Armor
Rebirth Upon taking lethal damage, restores 50% base Health and 100% max Mana after 4 seconds of Stasis.
Abilities & Skill Path

Deadly Venom
Twitch's basic attacks infect the target %i:OnHit% On-Hit, dealing true damage each second.
QAmbush
Cooldown 16s · 40 Mana
Twitch becomes Camouflaged for a short duration and gains Move Speed. When leaving Camouflage, Twitch gains Attack Speed for a short duration. When an enemy champion with Deadly Venom dies, Ambush's cooldown is reset.
WVenom Cask
Cooldown 13/12/11/10/9s · 70 Mana
Twitch hurls a cask of venom that explodes in an area, slowing targets and applying deadly venom to the target.
EContaminate
Cooldown 12/11/10/9/8s · 50/60/70/80/90 Mana
Twitch wreaks further havoc on poisoned enemies with a blast of his vile diseases.
RSpray and Pray
Cooldown 90s · 100 Mana
Twitch unleashes the full power of his crossbow, shooting bolts over a great distance that pierce all enemies caught in their path.